1. Pharmaceutical Intermediates
Bortezomib Acid Impurity: This is certainly an impurity related to bortezomib, a proteasome inhibitor Employed in the therapy of a number of myeloma. Its synthesis or review is critical for making certain the purity and safety with the drug.
Abiraterone Acetate Intermediate (CAS NO. 122111-01-7): A precursor while in the synthesis of abiraterone acetate, a drug used in the treatment of prostate most cancers by inhibiting androgen output.
Imatinib Intermediate (CAS NO. 152460-ten-one): A essential compound within the synthesis of imatinib, a drug that targets precise different types of most cancers, which includes chronic myelogenous leukemia (CML).
Docetaxel Intermediate: A compound Utilized in the synthesis of docetaxel, a chemotherapy medication that treats numerous cancers like breast, lung, and prostate most cancers.
2. Chemical Impurities and Byproducts
GeMcitabine Intermediates (T6, T9, eight): These are generally intermediates within the synthesis of gemcitabine, an anti-cancer drug. Their research is crucial for optimizing the creation system and making certain superior purity.
Lapatinib Intermediate (CAS NO. 231278-84-5): Lapatinib is made use of to treat breast cancer, and these intermediates are linked to its manufacturing.
Fulvestrant Intermediates: Fulvestrant is really an estrogen receptor antagonist used in the treatment method of breast most cancers. Numerous intermediates assist in the synthesis of this drug.
Paclitaxel Aspect Chain Acid (CAS NO. 949023-sixteen-nine): This intermediate is Employed in the synthesis of paclitaxel, a chemotherapy drug powerful Bortezomib Acid Impurity in managing cancers which include ovarian, breast, and lung cancer.
3. Other Notable Compounds
Irinotecan Hydrochloride Trihydrate (CAS NO. 136572-09-three): A chemotherapy drug Employed in the remedy of colorectal most cancers and compact mobile lung most cancers.
three-Amino-one-hydroxyadamantane (CAS 702-eighty two-nine): This compound is involved in the synthesis of adamantane derivatives, which have different programs, which include antiviral Attributes.
Vildagliptin Intermediates: Employed in the creation of vildagliptin, an oral drug for type two diabetic issues that inhibits the enzyme DPP-four to control blood sugar levels.
four. Miscellaneous Compounds
D-Gluconic Acid δ-Lactone (CAS NO. Dasatinib intermediate 61259-forty eight-one): This compound is involved with the synthesis of varied gluconic acid derivatives, that are Employed in foods, pharmaceutical, and industrial programs.
Canagliflozin Intermediate two: A precursor in the synthesis of canagliflozin, a medication employed to control variety 2 diabetes by inhibiting sodium-glucose co-transporter 2 (SGLT2).